The First Amendment of our beloved Constitution gives all the citizens the right to free speech.  When this right was first exercised by those in possession of printing presses, the opinion of one person was able to be quickly (relatively) disseminated to curious minds across the country.  The result of this combination was disastrous for some and emancipating for others.

“Off-label use” is a term that applies to any clinical use of an FDA approved medication or device that is not in accordance with labeling approved by the FDA.  While the off-label use of medications is both legal and very common (one study showed off-label use of medications in the primary care setting was as high as 20% and in some settings the majority of use was off-label), it is a violation of federal law for a manufacturer to advertise the use of a medication or device for any purpose not approved by the FDA.